Pemeriksaan Rutin Asam Urat dalam Rangka Pencegahan Timbulnya Arthritis Gout pada Kelompok Usia Produktif di Wilayah Krendang
DOI:
https://doi.org/10.59603/jpmnt.v3i1.667Keywords:
uric acid, healthy lifestyle, routine screening, prevention, community serviceAbstract
Uric acid is a byproduct of purine metabolism in the body, typically excreted through urine. However, excessive uric acid can lead to the accumulation of crystals in the joints, resulting in gouty arthritis, particularly in individuals of productive age. This article aims to discuss a community service initiative to prevent elevated uric acid levels through routine screenings and education on healthy lifestyles. The initiative employed the PDCA (Plan-Do-Check-Act) approach, encompassing counseling, uric acid level examinations, and iterative evaluations, thereby enhancing public awareness of the importance of maintaining normal uric acid levels and understanding healthy lifestyle practices. Education and early detection of uric acid levels can help the community comprehend actionable steps to reduce the risk of long-term health complications.
References
Asahina, Y., Sakaguchi, Y., Oka, T., Hattori, K., Kawaoka, T., Doi, Y., Yamamoto, R., Matsui, I., Mizui, M., Kaimori, J.-Y., & Isaka, Y. (2024). Association Between Urinary Uric Acid Excretion and Kidney Outcome in Patients With CKD. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-55809-9
Bailey, C. J. (2019). Uric Acid and the Cardio‐renal Effects of SGLT2 Inhibitors. Diabetes Obesity and Metabolism, 21(6), 1291–1298. https://doi.org/10.1111/dom.13670
Bellomo, G., & Selvi, A. (2018). Uric Acid: The Lower the Better? https://doi.org/10.1159/000484280
Borghi, C., Rosei, E. A., Bardin, T., Dawson, J., Dominiczak, A. F., Kielstein, J. T., Manolis, A., Pérez-Ruiz, F., & Mancia, G. (2015). Serum Uric Acid and the Risk of Cardiovascular and Renal Disease. Journal of Hypertension, 33(9), 1729–1741. https://doi.org/10.1097/hjh.0000000000000701
Browne, L. D., Jaouimaa, F.-Z., Walsh, C., Pérez-Ruiz, F., Richette, P., Burke, K., & Stack, A. G. (2021). Serum Uric Acid and Mortality Thresholds Among Men and Women in the Irish Health System: A Cohort Study. European Journal of Internal Medicine, 84, 46–55. https://doi.org/10.1016/j.ejim.2020.10.001
Cimmino, G., Gallinoro, E., Serafino, L. Di, Rosa, G. De, Sugraliyev, A., Golino, P., & Cirillo, P. (2023). Uric Acid Plasma Levels Are Associated With C-Reactive Protein Concentrations and the Extent of Coronary Artery Lesions in Patients With Acute Coronary Syndromes. Internal and Emergency Medicine, 18(6), 1751–1757. https://doi.org/10.1007/s11739-023-03360-2
Crişan, T. O., Cleophas, M. C. P., Novakovic, B., Erler, K., Veerdonk, F. L. van de, Stunnenberg, H. G., Netea, M. G., Dinarello, C. A., & Joosten, L. A. B. (2017). Uric Acid Priming in Human Monocytes Is Driven by the AKT–PRAS40 Autophagy Pathway. Proceedings of the National Academy of Sciences, 114(21), 5485–5490. https://doi.org/10.1073/pnas.1620910114
Din, U. A. A. S. El, Salem, M. M., & Abdulazim, D. O. (2017). Uric Acid in the Pathogenesis of Metabolic, Renal, and Cardiovascular Diseases: A Review. Journal of Advanced Research, 8(5), 537–548. https://doi.org/10.1016/j.jare.2016.11.004
Ernawati, E., Adjie, E. K. K., Firmansyah, Y., Yogie, G. S., Setyanegara, W. G., & Kurniawan, J. (2023). Pengaruh Kadar Profil Lipid, Asam Urat, Indeks Massa Tubuh, Tekanan Darah, dan Kadar Gula Darah Terhadap Penurunan Kapasitas Vital Paru pada Pekerja Usia Produktif. Malahayati Nursing Journal. https://api.semanticscholar.org/CorpusID:260389865
Hahn, K., Kanbay, M., Lanaspa, M. A., Johnson, R. J., & Ejaz, A. A. (2017). Serum Uric Acid and Acute Kidney Injury: A Mini Review. Journal of Advanced Research, 8(5), 529–536. https://doi.org/10.1016/j.jare.2016.09.006
Hanai, K., Tauchi, E., Nishiwaki, Y., Mori, T., Yokoyama, Y., Uchigata, Y., & Babazono, T. (2018). Effects of Uric Acid on Kidney Function Decline Differ Depending on Baseline Kidney Function in Type 2 Diabetic Patients. Nephrology Dialysis Transplantation. https://doi.org/10.1093/ndt/gfy138
Imasuen, U. J., Swanson, K. J., & Parajuli, S. (2023). Serum Uric Acid Levels in Kidney Transplant Recipients: A Cause for Concern? A Review of Recent Literature. Transplantation Reviews, 37(3), 100775. https://doi.org/10.1016/j.trre.2023.100775
Jeong, H. Y., Cho, H. J., Kim, S. H., Kim, J. C., Lee, M. J., Yang, D. H., & Lee, S. (2017). Association of Serum Uric Acid Level With Coronary Artery Stenosis Severity in Korean End-Stage Renal Disease Patients. Kidney Research and Clinical Practice, 36(3), 282–289. https://doi.org/10.23876/j.krcp.2017.36.3.282
Kaewput, W., Rangsin, R., Ruangkanchanasetr, P., Mao, M. A., & Cheungpasitporn, W. (2019). Association Between Serum Uric Acid and Chronic Kidney Disease in Patients With Hypertension: A Multicenter Nationwide Cross‐sectional Study. Journal of Evidence-Based Medicine, 12(4), 235–242. https://doi.org/10.1111/jebm.12364
Kang, D. H., & Johnson, R. J. (2015). Uric Acid Metabolism and the Kidney. https://doi.org/10.1016/b978-0-12-411602-3.00035-4
Karava, V., Dotis, J., Kondou, A., Christoforidis, A., Liakopoulos, V., Tsioni, K., Kollios, K., Papachristou, F., & Printza, N. (2020). Association Between Relative Fat Mass, Uric Acid, and Insulin Resistance in Children With Chronic Kidney Disease. Pediatric Nephrology, 36(2), 425–434. https://doi.org/10.1007/s00467-020-04716-y
Kaushik, M., & Choo, J. C. J. (2015). Serum Uric Acid and AKI: Is It Time? Clinical Kidney Journal, 9(1), 48–50. https://doi.org/10.1093/ckj/sfv127
Li, F., Guo, H., Zou, J., Chen, W., Lu, Y., Zhang, X., Fu, C., Xiao, J., & Ye, Z. (2018). The Association of Urinary Sodium and Potassium With Renal Uric Acid Excretion in Patients With Chronic Kidney Disease. Kidney and Blood Pressure Research, 43(4), 1310–1321. https://doi.org/10.1159/000492590
Luo, Y., Wu, Q., Meng, R., Lian, F., Jiang, C., Hu, M., Wang, Y., & Ma, H. (2023). Serum Uric Acid Levels and Their Association With Renal Function Decline and Kidney Disease Progression in Middle-Aged and Elderly Populations: A Retrospective Cohort Study. Journal of Multidisciplinary Healthcare, Volume 16, 3357–3366. https://doi.org/10.2147/jmdh.s435537
Qin, X., Qian, Z., Vaughn, M. G., Huang, J., Ward, P., Zeng, X. W., Zhou, Y., Zhu, Y., Yuan, P., Li, M., Zhang, B., Paul, G., Hao, Y., Chen, W., Chen, P., Dong, G., & Lee, Y. L. (2016). Positive Associations of Serum Perfluoroalkyl Substances With Uric Acid and Hyperuricemia in Children From Taiwan. Environmental Pollution, 212, 519–524. https://doi.org/10.1016/j.envpol.2016.02.050
Rhone, E. T., & Carmody, J. (2017). Birthweight and Serum Uric Acid in American Adolescents. Pediatrics International, 59(8), 948–950. https://doi.org/10.1111/ped.13328
Rodríguez-Arias, J.-J., & Coll‐de‐Tuero, G. (2015). Could Uric Acid Be Considered a Cardiovascular Risk Factor? Journal of Clinical Hypertension, 17(12), 936–937. https://doi.org/10.1111/jch.12636
Sari, T., Lumintang, V. G., Sukianto, L. A., Edbert, B., Gunaidi, F. C., & Santoso, A. H. (2024). Kegiatan Penapisan Pemeriksaan Kadar Asam Urat terhadap Hiperurisemia pada Populasi Lanjut Usia. Jurnal Pengabdian Masyarakat, 3(1), 201–206.
Seibert, H., Pereira, A. M. L., Pestana, J. O. M., & Nogueira, P. C. K. (2024). Serum Uric Acid Concentration Is Associated With Lower Glomerular Filtration Rate in Children Undergoing Kidney Transplantation. Pediatric Transplantation, 28(1). https://doi.org/10.1111/petr.14683
Smith, W. B., Hall, J., Berg, J. K., Kazimir, M., Yamamoto, A., Walker, S., Lee, C. A., Shen, Z., Wilson, D. M., Zhou, D., Gillen, M., & Marbury, T. (2018). Effect of Renal Impairment on the Pharmacokinetics and Pharmacodynamics of Verinurad, a Selective Uric Acid Reabsorption Inhibitor. Clinical Drug Investigation, 38(8), 703–713. https://doi.org/10.1007/s40261-018-0652-2
Treviño–Becerra, A. (2018). Uric Acid: The Unknown Uremic Toxin. https://doi.org/10.1159/000484275
Uchida, S., Kumagai, T., Chang, W., Tamura, Y., & Shibata, S. (2018). Time to Target Uric Acid to Retard Chronic Kidney Disease Progression. https://doi.org/10.1159/000484279
Wen, S., Arakawa, H., & Tamai, I. (2024). Uric Acid in Health and Disease: From Physiological Functions to Pathogenic Mechanisms. Pharmacology & Therapeutics, 256, 108615. https://doi.org/10.1016/j.pharmthera.2024.108615
Widjaja, Y., Kurniawan, J., Marcella, A., & Firmansyah, Y. (2023). Kewaspadaan penyakit dementia melalui edukasi gaya hidup dan skrining albuminuria, low-density lipoprotein (LDL), serta asam urat. SEWAGATI: Jurnal Pengabdian Masyarakat Indonesia, 2(2), 24–36.
Xiang, S., Zhang, X., Xie, X., Zhou, Q., Chen, Z., Wang, Y., Liu, G., Han, F., & Chen, J. (2019). High Serum Uric Acid Level Is a Mortality Risk Factor in Peritoneal Dialysis Patients: A Retrospective Cohort Study. Nutrition & Metabolism, 16(1). https://doi.org/10.1186/s12986-019-0379-y
Zhang, J., Pan, M., Zhang, J., You, X., Li, D., Lin, F., & Lu, G. (2019). Serum Uric Acid Is an Independent Predictor of Renal Outcomes in Patients With Idiopathic Membranous Nephropathy. International Urology and Nephrology, 51(10), 1797–1804. https://doi.org/10.1007/s11255-019-02254-7
Zhu, P., Liu, Y., Han, L., Xu, G., & Ran, J. (2014). Serum Uric Acid Is Associated With Incident Chronic Kidney Disease in Middle-Aged Populations: A Meta-Analysis of 15 Cohort Studies. Plos One, 9(6), e100801. https://doi.org/10.1371/journal.pone.0100801
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Jurnal Pengabdian Masyarakat Nian Tana
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.